Vitamin b12 Injection.
Cyanocobalamin is the most widely used form of the vitamin B12, and has hematopoietic activity apparently identical to that of the anti-anemia factor in purified liver extract. Hydroxycobalamin is equally as effective as cyanocobalamin, and they share the cobalamin molecular structure. Iron replacement can be given as a treatment for general anemia, but not for pernicious anemia. For pernicious anemia, vitamin B12 injections (called cyanocobalamin or hydroxyocobalamin), oral folic acid therapy, or both, can reverse the production of abnormal blood cells.
To deal with acute situations, Vitamin B12 injections are given daily for several weeks, then twice a week for a month, and monthly thereafter. Usually, the Vitamin B12 injections must be taken for life, although some patients can be maintained on an orally administered form of the Vitamin B12. It's difficult for the people to take monthly B12 injections, so other forms are being investigated. In Europe, a nasal spray form of the vitamin b12, hydroxocobalamin is showing promise and is expected to reach the U.S. soon.
Many Vitamin B12 injections (Cyanocobalamin) under various Brand names such as Cobal, Cyanoject, Cyomin, Vibal, Vitamin B-12 etc are available in market. Vitamin B12 injections help the body use fat and carbohydrates for energy and make new protein. It is also important for normal blood, cells, and nerves. Most people get enough of the vitamin B12 in their diet, but a deficiency may occur in certain health conditions (e.g., pernicious anemia), poor nutrition, stomach/intestinal problems, infection (cancer). Serious vitamin B12 deficiency may result in anemia, stomach problems, and nerve damage.
Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. This Vitamin B12 medication is given by injection into a muscle or under the skin as directed by your doctor. Dosage is based on your medical condition and response to treatment. Injections of Vitamin B12 may be given daily when you first start treatment.
A very serious allergic reaction to this Vitamin B12 drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction. Before using Vitamin B12 injection (cyanocobalamin), tell your doctor or pharmacist if you are allergic to it; or to cobalt; or if you have any other allergies. Your doctor may recommend that you receive a smaller test dose of the vitamin B12 before starting your regular dose. This product may contain inactive ingredients, which can cause allergic reactions or other problems. This product may contain aluminum, which can infrequently build up to dangerous levels in the body. The risk may be increased if this product is used for an extended time, especially in newborns or in people with kidney disease. Tell your doctor immediately if you notice any symptoms of too much aluminum in the body such as muscle weakness, bone pain, or mental changes. During pregnancy Vitamin B12 medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Based on information from related drugs, Vitamin B12 medication may pass into breast milk. Remember that your doctor has prescribed this Vitamin B12 medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this Vitamin B12 medication do not have serious side effects. This Vitamin B12 medication may cause low potassium levels in the blood (hypokalemia). Tell your doctor immediately if any of these unlikely but serious side effects occur. Muscle cramps, weakness, irregular heartbeat. People who have a rare blood disorder may infrequently have symptoms related to this disorder while taking Vitamin B12 injection (cyanocobalamin). This is not a complete list of possible side effects.
In a few instances, the underlying cause of the Vitamin B12 deficiency can be permanently corrected, e.g., the fish tapeworm, tropical sprue, or an intestinal stagnant loop that is amenable to surgery. The indications for starting Vitamin B12 therapy are a well-documented megaloblastic anemia or other hematologic abnormalities or neuropathy due to the Vitamin B12 deficiency. Patients with borderline serum Vitamin B12 levels but no hematologic or other abnormality should be followed up, e.g., at yearly intervals to make sure that the Vitamin B12 deficiency does not progress. If mal-absorptions of Vitamin B12 or rise in serum MMA levels have been demonstrated, then, they should also be given regular maintenance cobalamin Vitamin B12 therapy. Vitamin B12 should be given routinely to all patients who have had a total gastrectomy or ileal resection. Patients who have undergone gastric reduction for control of obesity or who are receiving long-term treatment with proton pump inhibitors, should be screened and, if necessary, given Vitamin B12 replacement.
